National Bioterrorism Syndromic Surveillance Demonstration Project 
Supported by the National Center for Infectious Diseases
Centers for Disease Control and Prevention
(Grant UR/CCU115079)

Centers for Disease Control and Prevention | Harvard Pilgrim Health Care | Channing Laboratory | Harvard Medical School | American Association of Health Plans



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Surveillance Reports of Syndromic Episodes
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Time Series Charts Surveillance Maps

Amalgamated National Counts
Colorado
Massachusetts
Minnesota
Texas
San Mateo County

US National
Colorado
Massachusetts
Minnesota
Texas
San Mateo County


Purpose
National coverage of information from ambulatory visits and calls to nurse help lines for over 20 million people is collected each day, analyzed and used to identify unusual clusters of illness that might represent bioterrorism events or other outbreaks of public health importance.

The Data
Participating health plans transmit data on a daily basis to the data-coordinating center at the Channing Laboratory. This data consists of the aggregate number of encounters (patient visits or calls) for new episodes of illness categorized by zip code of residence and by syndrome. Encounter-level data remains at the health plan, preserving the integrity of patient privacy.

Identifying Unusual Clusters of Illness
Statistical models are used to assign a significance level to the aggregate numbers of encounters to identify unusual clusters of illness. These models account for the type of illness, geographic region, and month of year and day of week on which the encounter occurred. They allow participating state and local health departments to identify and focus on clusters that exceed whatever threshold they consider important. Public health personnel can elect to be automatically notified of clusters exceeding these specified thresholds and thus alerted to potential bioterrorism activity.

An example cluster in Massachusetts

Participating Organizations
All Participants

Organizations and communities interested in participating can send requests for information to the program administrative officer.

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Bioterrorism Collage

Selected Publications

1. A model-adjusted space-time scan statistic for syndromic surveillance.
To appear in Epidemiol Infect 2005.

2. The National Bioterrorism Syndromic Surveillance Demonstration Program.
MMWR, 2004

3. Using minimally identifiable data for syndromic surveillance.
Journ. of Urb. Health 2003

4. Use of automated ambulatory-care encounter records for detection of acute illness clusters.
Emerg Infect Dis, 2002.

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